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Hyaluronic acid enhances cell migration and invasion via the YAP1/TAZ-RHAMM axis in malignant pleural mesothelioma

Most malignant mesotheliomas (MPMs) frequently show activated forms of Yes-associated protein 1 (YAP1) and transcriptional co-activator with PDZ-binding motif (TAZ), which transcriptionally regulates the receptor for hyaluronic acid-mediated motility (RHAMM). As RHAMM is involved in cell migration a...

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Detalles Bibliográficos
Autores principales: Shigeeda, Wataru, Shibazaki, Masahiko, Yasuhira, Shinji, Masuda, Tomoyuki, Tanita, Tatsuo, Kaneko, Yuka, Sato, Tatsuhiro, Sekido, Yoshitaka, Maesawa, Chihaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706831/
https://www.ncbi.nlm.nih.gov/pubmed/29212185
http://dx.doi.org/10.18632/oncotarget.20750