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α7 nAChR mediated Fas demethylation contributes to prenatal nicotine exposure-induced programmed thymocyte apoptosis in mice

This study aimed to investigate the effects of prenatal nicotine exposure (PNE) on thymocyte apoptosis and postnatal immune impairments in vivo and further explore the epigenetic mechanisms of the pro-apoptotic effect of nicotine in vitro. The results showed that PNE caused immune impairments in off...

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Detalles Bibliográficos
Autores principales: Liu, Han-Xiao, Liu, Sha, Qu, Wen, Yan, Hui-Yi, Wen, Xiao, Chen, Ting, Hou, Li-Fang, Ping, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706832/
https://www.ncbi.nlm.nih.gov/pubmed/29212186
http://dx.doi.org/10.18632/oncotarget.21526