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Association between miR-31-3p expression and cetuximab efficacy in patients with KRAS wild-type metastatic colorectal cancer: a post-hoc analysis of the New EPOC trial

BACKGROUND: High miR-31-3p expression is associated with inferior outcomes in KRAS wild-type (WT) advanced colorectal cancer patients treated with anti-EGFR therapy. This study evaluated miR-31-3p expression in patients with operable colorectal liver metastases (LM) enrolled in the New EPOC study. M...

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Detalles Bibliográficos
Autores principales: Pugh, Siân, Thiébaut, Raphaële, Bridgewater, John, Grisoni, Marie-Lise, Moutasim, Karwan, Rousseau, Francis, Thomas, Gareth J., Griffiths, Gareth, Liebaert, François, Primrose, John, Laurent-Puig, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706840/
https://www.ncbi.nlm.nih.gov/pubmed/29212194
http://dx.doi.org/10.18632/oncotarget.21291