miR-21 silencing ameliorates experimental autoimmune encephalomyelitis by promoting the differentiation of IL-10-producing B cells

IL-10-producing regulatory B (IL-10(+) Breg) cells promote tolerance in autoimmune diseases and transplantation. However, it remains unclear whether microRNAs are involved in the development of IL-10(+) Breg cells. Here, we found that microRNA-21 (miR-21) acts as an upstream regulator of IL-10 by ta...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Xu, Wenrong, Shao, Qixiang, Ding, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706856/
https://www.ncbi.nlm.nih.gov/pubmed/29212210
http://dx.doi.org/10.18632/oncotarget.21578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706856/
https://www.ncbi.nlm.nih.gov/pubmed/29212210
http://dx.doi.org/10.18632/oncotarget.21578

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