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miR-21 silencing ameliorates experimental autoimmune encephalomyelitis by promoting the differentiation of IL-10-producing B cells
IL-10-producing regulatory B (IL-10(+) Breg) cells promote tolerance in autoimmune diseases and transplantation. However, it remains unclear whether microRNAs are involved in the development of IL-10(+) Breg cells. Here, we found that microRNA-21 (miR-21) acts as an upstream regulator of IL-10 by ta...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706856/ https://www.ncbi.nlm.nih.gov/pubmed/29212210 http://dx.doi.org/10.18632/oncotarget.21578 |