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Betanodavirus B2 protein triggers apoptosis and necroptosis in lung cancer cells that suppresses autophagy

The betanodavirus B2 protein targets the mitochondria and acts as a “death factor”, but its effect on lung cancer cells is unknown. We examined the effect of the B2 protein on triggering apoptosis or necroptosis via P53-dependent and P53-independent pathways and increased in suppression of autophagy...

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Detalles Bibliográficos
Autores principales: Chiu, Hsuan-Wen, Su, Yu-Chin, Hong, Jiann-Ruey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706861/
https://www.ncbi.nlm.nih.gov/pubmed/29212215
http://dx.doi.org/10.18632/oncotarget.21588