Optimized guide RNA structure for genome editing via Cas9

The genome editing tool Cas9-gRNA (guide RNA) has been successfully applied in different cell types and organisms with high efficiency. However, more efforts need to be made to enhance both efficiency and specificity. In the current study, we optimized the guide RNA structure of Streptococcus pyogen...

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Detalles Bibliográficos
Autores principales: Xu, Jianyong, Lian, Wei, Jia, Yuning, Li, Lingyun, Huang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706864/
https://www.ncbi.nlm.nih.gov/pubmed/29212218
http://dx.doi.org/10.18632/oncotarget.21607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706864/
https://www.ncbi.nlm.nih.gov/pubmed/29212218
http://dx.doi.org/10.18632/oncotarget.21607

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