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Antitumor activity of a newly developed monoclonal antibody against ROR1 in ovarian cancer cells

Receptor-tyrosine-kinase-like Orphan Receptor 1 (ROR1) is a tyrosine-protein kinase transmembrane receptor and ROR1 overexpression is associated with a poor prognosis in various cancers, including ovarian cancer. Targeting of ROR1 has been evaluated as a novel cancer therapy strategy. This study dev...

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Detalles Bibliográficos
Autores principales: Yin, Zhengna, Gao, Mengyun, Chu, Sasa, Su, Yiping, Ye, Chunping, Wang, Yiquan, Pan, Zhuanqin, Wang, Zhuming, Zhang, Huilin, Tong, Hua, Zhu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706868/
https://www.ncbi.nlm.nih.gov/pubmed/29212222
http://dx.doi.org/10.18632/oncotarget.21618