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HADC5 deacetylates MKL1 to dampen TNF-α induced pro-inflammatory gene transcription in macrophages

Macrophage-dependent inflammatory response on the one hand functions as a key line of defense in host immunity but on the other hand underlies the pathogenesis of a host of human pathologies when aberrantly activated. Our previous investigations have led to the identification of megakaryocytic leuke...

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Detalles Bibliográficos
Autores principales: Li, Zilong, Qin, Hao, Li, Jianfei, Yu, Liming, Yang, Yuyu, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706870/
https://www.ncbi.nlm.nih.gov/pubmed/29212224
http://dx.doi.org/10.18632/oncotarget.21670