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Transcribed ultraconserved region Uc.63+ promotes resistance to docetaxel through regulation of androgen receptor signaling in prostate cancer

Docetaxel is the standard chemotherapy for metastatic castration-resistant prostate cancer (CRPC). However, nearly all patients ultimately become refractory due to the development of docetaxel resistance. The transcribed ultraconserved regions (T-UCRs) are a novel class of non-coding RNAs that are a...

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Detalles Bibliográficos
Autores principales: Sekino, Yohei, Sakamoto, Naoya, Goto, Keisuke, Honma, Ririno, Shigematsu, Yoshinori, Sentani, Kazuhiro, Oue, Naohide, Teishima, Jun, Matsubara, Akio, Yasui, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706872/
https://www.ncbi.nlm.nih.gov/pubmed/29212226
http://dx.doi.org/10.18632/oncotarget.21688