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Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling

Expression of the inflammatory cytokine growth differentiation factor 15 (GDF15) is significantly elevated in many tumor types in association with epithelial mesenchymal transition (EMT), drug resistance, and progressive disease. However, few studies have examined GDF15 expression, signaling, or fun...

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Detalles Bibliográficos
Autores principales: Peake, Bridgette F., Eze, Siobhan M., Yang, Lily, Castellino, Robert C., Nahta, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706882/
https://www.ncbi.nlm.nih.gov/pubmed/29212236
http://dx.doi.org/10.18632/oncotarget.21765