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Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling
Expression of the inflammatory cytokine growth differentiation factor 15 (GDF15) is significantly elevated in many tumor types in association with epithelial mesenchymal transition (EMT), drug resistance, and progressive disease. However, few studies have examined GDF15 expression, signaling, or fun...
Autores principales: | Peake, Bridgette F., Eze, Siobhan M., Yang, Lily, Castellino, Robert C., Nahta, Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706882/ https://www.ncbi.nlm.nih.gov/pubmed/29212236 http://dx.doi.org/10.18632/oncotarget.21765 |
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