Distinct mobilization of leukocytes and hematopoietic stem cells by CXCR4 peptide antagonist LY2510924 and monoclonal antibody LY2624587

Stromal cell-derived factor-1 (SDF-1) and its receptor CXCR4 play a critical role in mobilization and redistribution of immune cells and hematopoietic stem cells (HSCs). We evaluated effects of two CXCR4-targeting agents, peptide antagonist LY2510924 and monoclonal antibody LY2624587, on mobilizing...

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Detalles Bibliográficos
Autores principales: Peng, Sheng-Bin, Van Horn, Robert D., Yin, Tinggui, Brown, Robin M., Roell, William C., Obungu, Victor H., Ruegg, Charles, Wroblewski, Victor J., Raddad, Eyas, Stille, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706900/
https://www.ncbi.nlm.nih.gov/pubmed/29212254
http://dx.doi.org/10.18632/oncotarget.21816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706900/
https://www.ncbi.nlm.nih.gov/pubmed/29212254
http://dx.doi.org/10.18632/oncotarget.21816

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