Cordycepin stimulates autophagy in macrophages and prevents atherosclerotic plaque formation in ApoE(-/-) mice

Autophagy in macrophages plays a key role in the pathogenesis and progression of atherosclerosis and has become a potential therapeutic target. Here we show that cordycepin (Cpn), a natural derivative of adenosine, markedly reduced atherosclerotic plaque and ameliorated associated symptoms such as d...

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Detalles Bibliográficos
Autores principales: Li, Xin, Zhou, Yue, Zhang, Xue, Cao, Xiaoxue, Wu, Chongming, Guo, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706907/
https://www.ncbi.nlm.nih.gov/pubmed/29212261
http://dx.doi.org/10.18632/oncotarget.21886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706907/
https://www.ncbi.nlm.nih.gov/pubmed/29212261
http://dx.doi.org/10.18632/oncotarget.21886

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