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Cordycepin stimulates autophagy in macrophages and prevents atherosclerotic plaque formation in ApoE(-/-) mice
Autophagy in macrophages plays a key role in the pathogenesis and progression of atherosclerosis and has become a potential therapeutic target. Here we show that cordycepin (Cpn), a natural derivative of adenosine, markedly reduced atherosclerotic plaque and ameliorated associated symptoms such as d...
Autores principales: | Li, Xin, Zhou, Yue, Zhang, Xue, Cao, Xiaoxue, Wu, Chongming, Guo, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706907/ https://www.ncbi.nlm.nih.gov/pubmed/29212261 http://dx.doi.org/10.18632/oncotarget.21886 |
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