Activation of Discs large by aPKC aligns the mitotic spindle to the polarity axis during asymmetric cell division

Asymmetric division generates cellular diversity by producing daughter cells with different fates. In animals, the mitotic spindle aligns with Par complex polarized fate determinants, ensuring that fate determinant cortical domains are bisected by the cleavage furrow. Here, we investigate the mechan...

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Detalles Bibliográficos
Autores principales: Golub, Ognjen, Wee, Brett, Newman, Rhonda A, Paterson, Nicole M, Prehoda, Kenneth E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706957/
https://www.ncbi.nlm.nih.gov/pubmed/29185419
http://dx.doi.org/10.7554/eLife.32137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706957/
https://www.ncbi.nlm.nih.gov/pubmed/29185419
http://dx.doi.org/10.7554/eLife.32137

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