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Activation of Discs large by aPKC aligns the mitotic spindle to the polarity axis during asymmetric cell division
Asymmetric division generates cellular diversity by producing daughter cells with different fates. In animals, the mitotic spindle aligns with Par complex polarized fate determinants, ensuring that fate determinant cortical domains are bisected by the cleavage furrow. Here, we investigate the mechan...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706957/ https://www.ncbi.nlm.nih.gov/pubmed/29185419 http://dx.doi.org/10.7554/eLife.32137 |