Cargando…

Ubiquitin turnover and endocytic trafficking in yeast are regulated by Ser57 phosphorylation of ubiquitin

Despite its central role in protein degradation little is known about the molecular mechanisms that sense, maintain, and regulate steady state concentration of ubiquitin in the cell. Here, we describe a novel mechanism for regulation of ubiquitin homeostasis that is mediated by phosphorylation of ub...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Sora, Tumolo, Jessica M, Ehlinger, Aaron C, Jernigan, Kristin K, Qualls-Histed, Susan J, Hsu, Pi-Chiang, McDonald, W Hayes, Chazin, Walter J, MacGurn, Jason A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706963/
https://www.ncbi.nlm.nih.gov/pubmed/29130884
http://dx.doi.org/10.7554/eLife.29176