Cargando…

Phosphorylation regulates connexin43/ZO-1 binding and release, an important step in gap junction turnover

To investigate whether connexin phosphorylation regulates the known role of zonula occludens-1 protein (ZO-1) in gap junction (GJ) function, we generated and analyzed a series of phosphomimetic and phosphorylation-dead mutants by mutating known conserved regulatory serine (S) residues 255, 279/282,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thévenin, Anastasia F., Margraf, Rachel A., Fisher, Charles G., Kells-Andrews, Rachael M., Falk, Matthias M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706988/ https://www.ncbi.nlm.nih.gov/pubmed/29021339 http://dx.doi.org/10.1091/mbc.E16-07-0496

Ejemplares similares

Connexin43 phosphorylation by PKC and MAPK signals VEGF-mediated gap junction internalization
por: Nimlamool, Wutigri, et al.
Publicado: (2015)

Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1
por: Bruce, Alexandra F., et al.
Publicado: (2008)

Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells
Publicado: (1995)

Src Regulation of Cx43 Phosphorylation and Gap Junction Turnover
por: Solan, Joell L., et al.
Publicado: (2020)

Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques
Publicado: (1991)

Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines
Publicado: (1990)

Two tyrosine-based sorting signals in the Cx43 C-terminus cooperate to mediate gap junction endocytosis
por: Fong, John T., et al.
Publicado: (2013)

Phosphorylation of Connexin43 on Serine368 by Protein Kinase C Regulates Gap Junctional Communication
por: Lampe, Paul D., et al.
Publicado: (2000)

Role of Bcl2-associated Athanogene 3 in Turnover of Gap Junction Protein, Connexin 43, in Neonatal Cardiomyocytes
por: Ghasemi Tahrir, Farzaneh, et al.
Publicado: (2019)

Connexin43 and Bergmann Glial Gap Junctions in Cerebellar Function
por: Tanaka, Mika, et al.
Publicado: (2008)

Myosin VI facilitates connexin 43 gap junction accretion
por: Waxse, Bennett J., et al.
Publicado: (2017)

Gap Junction-Dependent and -Independent Functions of Connexin43 in Biology
por: Zhu, Yi
Publicado: (2022)

v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication
por: Lin, Rui, et al.
Publicado: (2001)

Histone deacetylase inhibition reduces cardiac connexin43 expression and gap junction communication
por: Xu, Qin, et al.
Publicado: (2013)

Transfected connexin45 alters gap junction permeability in cells expressing endogenous connexin43
Publicado: (1995)

Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation
por: Yamada, Aya, et al.
Publicado: (2021)

Betacellulin regulates gap junction intercellular communication by inducing the phosphorylation of connexin 43 in human granulosa-lutein cells
por: Li, Yuxi, et al.
Publicado: (2023)

Conductance and Permeability of the Residual State of Connexin43 Gap Junction Channels
por: Bukauskas, Feliksas F., et al.
Publicado: (2002)

AGE-BSA down-regulates endothelial connexin43 gap junctions
por: Wang, Chi-Young, et al.
Publicado: (2011)

Gap Junction Protein Connexin43 Exacerbates Lung Vascular Permeability
por: O’Donnell, James J., et al.
Publicado: (2014)

Connexin-43 Gap Junctions Are Responsible for the Hypothalamic Tanycyte-Coupled Network
por: Recabal, Antonia, et al.
Publicado: (2018)

A Mitosis-specific Phosphorylation of the Gap Junction Protein Connexin43 in Human Vascular Cells: Biochemical Characterization and Localization
por: Xie, Han-qing, et al.
Publicado: (1997)

Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells
por: Johnson, Kristen E., et al.
Publicado: (2013)

Cyclic AMP mediates ovine cumulus–oocyte gap junctional function via balancing connexin 43 expression and phosphorylation
por: Zhao, Yufen, et al.
Publicado: (2023)

Ser364 of connexin43 and the upregulation of gap junction assembly by cAMP
por: TenBroek, Erica M., et al.
Publicado: (2001)

Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate
por: van Zeijl, Leonie, et al.
Publicado: (2007)

Monovalent Ion Selectivity Sequences of the Rat Connexin43 Gap Junction Channel
por: Wang, Hong-Zhan, et al.
Publicado: (1997)

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1
por: Rhett, J. Matthew, et al.
Publicado: (2011)

Functional analysis of hemichannels and gap-junctional channels formed by connexins 43 and 46
por: Hoang, Quan V., et al.
Publicado: (2010)

Expression of gap junction proteins connexins 26, 30, and 43 in Dupuytren’s disease
por: Holzer, Lukas A, et al.
Publicado: (2014)

Role of Gap Junction Protein Connexin43 in Astrogliosis Induced by Brain Injury
por: Theodoric, Nicolas, et al.
Publicado: (2012)

Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention
por: Zhu, Yi, et al.
Publicado: (2022)

Structure of the connexin-43 gap junction channel in a putative closed state
por: Qi, Chao, et al.
Publicado: (2023)

Molecular mechanisms regulating formation, trafficking and processing of annular gap junctions
por: Falk, Matthias M., et al.
Publicado: (2016)

Influence of V5/6-His Tag on the Properties of Gap Junction Channels Composed of Connexin43, Connexin40 or Connexin45
por: Desplantez, Thomas, et al.
Publicado: (2011)

Gap junction assembly: roles for the formation plaque and regulation by the C-terminus of connexin43
por: Johnson, Ross G., et al.
Publicado: (2012)

Connexin 43 Expression on Peripheral Blood Eosinophils: Role of Gap Junctions in Transendothelial Migration
por: Vliagoftis, Harissios, et al.
Publicado: (2014)

Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43
por: Kam, Chen Yuan, et al.
Publicado: (2018)

Expression of Connexin43 Stimulates Endothelial Angiogenesis Independently of Gap Junctional Communication In Vitro
por: Koepple, Christoph, et al.
Publicado: (2021)

Connexin26 mutations causing palmoplantar keratoderma and deafness interact with connexin43, modifying gap junction and hemichannel properties
por: Shuja, Zunaira, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_266ovlbhisqfqsk0omcshnqcsd