Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair

We have previously identified a recurrent deletion at chromosomal band 3p14.1-p13 in patients with acute myeloid leukemia (AML). Among eight protein-coding genes, this microdeletion affects the protein phosphatase 4 regulatory subunit 2 (PPP4R2), which plays an important role in DNA damage response...

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Detalles Bibliográficos
Autores principales: Herzig, Julia K., Bullinger, Lars, Tasdogan, Alpaslan, Zimmermann, Philipp, Schlegel, Martin, Teleanu, Veronica, Weber, Daniela, Rücker, Frank G., Paschka, Peter, Dolnik, Anna, Schneider, Edith, Kuchenbauer, Florian, Heidel, Florian H., Buske, Christian, Döhner, Hartmut, Döhner, Konstanze, Gaidzik, Verena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707003/
https://www.ncbi.nlm.nih.gov/pubmed/29221109
http://dx.doi.org/10.18632/oncotarget.21119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707003/
https://www.ncbi.nlm.nih.gov/pubmed/29221109
http://dx.doi.org/10.18632/oncotarget.21119

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