Inhibition of chemerin/CMKLR1 axis in neuroblastoma cells reduces clonogenicity and cell viability in vitro and impairs tumor growth in vivo

Pro-inflammatory cells, cytokines, and chemokines are essential in promoting a tumor supporting microenvironment. Chemerin is a chemotactic protein and a natural ligand for the receptors CMKLR1, GPR1, and CCRL2. The chemerin/CMKLR1 axis is involved in immunity and inflammation, and it has also been...

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Detalles Bibliográficos
Autores principales: Tümmler, Conny, Snapkov, Igor, Wickström, Malin, Moens, Ugo, Ljungblad, Linda, Maria Elfman, Lotta Helena, Winberg, Jan-Olof, Kogner, Per, Johnsen, John Inge, Sveinbjørnsson, Baldur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707011/
https://www.ncbi.nlm.nih.gov/pubmed/29221117
http://dx.doi.org/10.18632/oncotarget.19619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707011/
https://www.ncbi.nlm.nih.gov/pubmed/29221117
http://dx.doi.org/10.18632/oncotarget.19619

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