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Hoxa5 increases mitochondrial apoptosis by inhibiting Akt/mTORC1/S6K1 pathway in mice white adipocytes

Homeobox A5(Hoxa5), a member of the Hox family, plays a important role in the regulation of proliferation and apoptosis in cancer cells. The dysregulation of the adipocyte apoptosis in vivo leads to obesity and metabolic disorders. However, the effects of Hoxa5 on adipocyte apoptosis are still unkno...

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Detalles Bibliográficos
Autores principales: Feng, Fei, Ren, Qian, Wu, Song, Saeed, Muhammad, Sun, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707025/
https://www.ncbi.nlm.nih.gov/pubmed/29221131
http://dx.doi.org/10.18632/oncotarget.20521