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Neuroprotection of Botch in experimental intracerebral hemorrhage in rats

Notch1 maturation participates in apoptosis and inflammation following intracerebral hemorrhage (ICH). It has been reported that Botch bound to and blocked Notch1 maturation. Here we estimated the role of Botch in ICH-induced secondary brain injury and underlying mechanisms. Experimental ICH model w...

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Detalles Bibliográficos
Autores principales: Mei, Binbin, Li, Haiying, Zhu, Juehua, Yang, Junjie, Yang, Ziying, Wen, Zunjia, Li, Xiang, Shen, Haitao, Shen, Meifen, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707026/
https://www.ncbi.nlm.nih.gov/pubmed/29221132
http://dx.doi.org/10.18632/oncotarget.20524