UCP2 overexpression enhanced glycolysis via activation of PFKFB2 during skin cell transformation

Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane transporter which is often upregulated in human cancers. However, how this anion transporter affects tumorigenesis is not well understood. Using the skin cell transformation JB6 model, we demonstrated that UCP2 overexpression activated p...

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Detalles Bibliográficos
Autores principales: Sreedhar, Annapoorna, Petruska, Petra, Miriyala, Sumitra, Panchatcharam, Manikandan, Zhao, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707038/
https://www.ncbi.nlm.nih.gov/pubmed/29221144
http://dx.doi.org/10.18632/oncotarget.20762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707038/
https://www.ncbi.nlm.nih.gov/pubmed/29221144
http://dx.doi.org/10.18632/oncotarget.20762

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