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UCP2 overexpression enhanced glycolysis via activation of PFKFB2 during skin cell transformation
Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane transporter which is often upregulated in human cancers. However, how this anion transporter affects tumorigenesis is not well understood. Using the skin cell transformation JB6 model, we demonstrated that UCP2 overexpression activated p...
Autores principales: | Sreedhar, Annapoorna, Petruska, Petra, Miriyala, Sumitra, Panchatcharam, Manikandan, Zhao, Yunfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707038/ https://www.ncbi.nlm.nih.gov/pubmed/29221144 http://dx.doi.org/10.18632/oncotarget.20762 |
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