Subependymal giant cell astrocytomas in Tuberous Sclerosis Complex have consistent TSC1/TSC2 biallelic inactivation, and no BRAF mutations

Subependymal giant cell astrocytomas (SEGAs) are rare, low-grade glioneuronal brain tumors that occur almost exclusively in patients with tuberous sclerosis complex (TSC). Though histologically benign, SEGAs can lead to serious neurological complications, including hydrocephalus, intractable seizure...

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Detalles Bibliográficos
Autores principales: Bongaarts, Anika, Giannikou, Krinio, Reinten, Roy J., Anink, Jasper J., Mills, James D., Jansen, Floor E., Spliet, G.M Wim, den Dunnen, Willfred F.A., Coras, Roland, Blümcke, Ingmar, Paulus, Werner, Scholl, Theresa, Feucht, Martha, Kotulska, Katarzyna, Jozwiak, Sergiusz, Buccoliero, Anna Maria, Caporalini, Chiara, Giordano, Flavio, Genitori, Lorenzo, Söylemezoğlu, Figen, Pimentel, José, Nellist, Mark, Schouten-van Meeteren, Antoinette Y.N., Nag, Anwesha, Mühlebner, Angelika, Kwiatkowski, David J., Aronica, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707039/
https://www.ncbi.nlm.nih.gov/pubmed/29221145
http://dx.doi.org/10.18632/oncotarget.20764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707039/
https://www.ncbi.nlm.nih.gov/pubmed/29221145
http://dx.doi.org/10.18632/oncotarget.20764

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