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Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples

Massively parallel DNA sequencing enables the detection of thousands of germline and somatic single nucleotide variants (SNVs) in cancer samples. The functional analysis of these mutations is often carried out through in silico predictions, with further downstream experimental validation rarely perf...

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Detalles Bibliográficos
Autores principales: Ma, Shiyong, Menon, Ranjeeta, Poulos, Rebecca C., Wong, Jason W.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707065/
https://www.ncbi.nlm.nih.gov/pubmed/29221171
http://dx.doi.org/10.18632/oncotarget.21339