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Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples
Massively parallel DNA sequencing enables the detection of thousands of germline and somatic single nucleotide variants (SNVs) in cancer samples. The functional analysis of these mutations is often carried out through in silico predictions, with further downstream experimental validation rarely perf...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707065/ https://www.ncbi.nlm.nih.gov/pubmed/29221171 http://dx.doi.org/10.18632/oncotarget.21339 |