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Farnesyl phenolic enantiomers as natural MTH1 inhibitors from Ganoderma sinense
Cancer cells are more addictive to MTH1 than normal cells because of their dysfunctional redox regulations. MTH1 plays an important role to maintain tumor cell survival, while it is not indispensable for the growth of normal cells. Farnesyl phenols having a coumaroyl substitution are rather uncommon...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707067/ https://www.ncbi.nlm.nih.gov/pubmed/29221173 http://dx.doi.org/10.18632/oncotarget.21430 |