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TRPM8 is required for survival and radioresistance of glioblastoma cells

TRPM8 is a Ca(2+)-permeable nonselective cation channel belonging to the melastatin sub-group of the transient receptor potential (TRP) family. TRPM8 is aberrantly overexpressed in a variety of tumor entities including glioblastoma multiforme where it reportedly contributes to tumor invasion. The pr...

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Detalles Bibliográficos
Autores principales: Klumpp, Dominik, Frank, Stephanie C., Klumpp, Lukas, Sezgin, Efe C., Eckert, Marita, Edalat, Lena, Bastmeyer, Martin, Zips, Daniel, Ruth, Peter, Huber, Stephan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707069/
https://www.ncbi.nlm.nih.gov/pubmed/29221175
http://dx.doi.org/10.18632/oncotarget.21436