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Functional FGFR4 Gly388Arg polymorphism contributes to oral squamous cell carcinoma susceptibility

Aberrations of the fibroblast growth factor receptor 4 (FGFR4) genomic region include amplification of FGFR4, activation of FGFR4 kinase domain mutations, and overexpression of FGFR4, which lead to sustained cell proliferation and contribute to tumor development. However, the association between FGF...

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Detalles Bibliográficos
Autores principales: Chou, Chia-Hsuan, Hsieh, Ming-Ju, Chuang, Chun-Yi, Lin, Jen-Tsun, Yeh, Chia-Ming, Tseng, Pao-Yu, Yang, Shun-Fa, Chen, Mu-Kuan, Lin, Chiao-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707095/
https://www.ncbi.nlm.nih.gov/pubmed/29221201
http://dx.doi.org/10.18632/oncotarget.21958