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Functional FGFR4 Gly388Arg polymorphism contributes to oral squamous cell carcinoma susceptibility
Aberrations of the fibroblast growth factor receptor 4 (FGFR4) genomic region include amplification of FGFR4, activation of FGFR4 kinase domain mutations, and overexpression of FGFR4, which lead to sustained cell proliferation and contribute to tumor development. However, the association between FGF...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707095/ https://www.ncbi.nlm.nih.gov/pubmed/29221201 http://dx.doi.org/10.18632/oncotarget.21958 |