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Methylated claudin-11 associated with metastasis and poor survival of colorectal cancer

As one of crucial epigenetic modification, DNA methylation plays an important role during the carcinogenesis of colorectal cancer (CRC). In the current study, we used a human genome methylation array to detect the aberrant methylation genes in CRC. We further identified the hypermethylation of claud...

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Detalles Bibliográficos
Autores principales: Li, Jinyun, Zhou, Chongchang, Ni, Shumin, Wang, Shaomin, Ni, Chao, Yang, Ping, Ye, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707097/
https://www.ncbi.nlm.nih.gov/pubmed/29221203
http://dx.doi.org/10.18632/oncotarget.21997