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DNMT1 overexpression predicting gastric carcinogenesis, subsequent progression and prognosis: a meta and bioinformatic analysis

DNMT1 is important in maintaining DNA methylation, and participates in the oncogenesis via up- or down-regulation leading to hyper-methylation or hypo-methylation. In the meta and bioinformatic analysis, we found that DNMT1 expression was higher in gastric cancer, compared with normal (p < 0.0000...

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Detalles Bibliográficos
Autores principales: Ma, Tianmiao, Li, Hao, Sun, Mingjun, Yuan, Yuan, Sun, Li-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707109/
https://www.ncbi.nlm.nih.gov/pubmed/29221215
http://dx.doi.org/10.18632/oncotarget.21480