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Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression

Angiocrine factors, such as Notch ligands, supplied by the specialized endothelial cells (ECs) within the bone marrow and splenic vascular niche play an essential role in modulating the physiology of adult hematopoietic stem and progenitor cells (HSPCs). However, the relative contribution of various...

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Detalles Bibliográficos
Autores principales: Guo, Peipei, Poulos, Michael G., Palikuqi, Brisa, Badwe, Chaitanya R., Lis, Raphael, Kunar, Balvir, Ding, Bi-Sen, Rabbany, Sina Y., Shido, Koji, Butler, Jason M., Rafii, Shahin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707154/
https://www.ncbi.nlm.nih.gov/pubmed/29058691
http://dx.doi.org/10.1172/JCI92309