NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription

Myosin VI (MVI) has been found to be overexpressed in ovarian, breast and prostate cancers. Moreover, it has been shown to play a role in regulating cell proliferation and migration, and to interact with RNA Polymerase II (RNAPII). Here, we find that backfolding of MVI regulates its ability to bind...

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Detalles Bibliográficos
Autores principales: Fili, Natalia, Hari-Gupta, Yukti, dos Santos, Ália, Cook, Alexander, Poland, Simon, Ameer-Beg, Simon M., Parsons, Maddy, Toseland, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707354/
https://www.ncbi.nlm.nih.gov/pubmed/29187741
http://dx.doi.org/10.1038/s41467-017-02050-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707354/
https://www.ncbi.nlm.nih.gov/pubmed/29187741
http://dx.doi.org/10.1038/s41467-017-02050-w

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