Antiphospholipid antibodies increase the levels of mitochondrial DNA in placental extracellular vesicles: Alarmin-g for preeclampsia

The pathogenesis of preeclampsia remains unclear but placental factors are known to play a crucial role causing maternal endothelial cell dysfunction. One potential factor is placental micro- and nano- vesicles. Antiphospholipid antibodies (aPL) increase the risk of preeclampsia ten-fold, in part by...

Descripción completa

Detalles Bibliográficos
Autores principales: Tong, Mancy, Johansson, Caroline, Xiao, Fengyi, Stone, Peter R., James, Joanna L., Chen, Qi, Cree, Lynsey M., Chamley, Lawrence W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707355/
https://www.ncbi.nlm.nih.gov/pubmed/29185455
http://dx.doi.org/10.1038/s41598-017-16448-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707355/
https://www.ncbi.nlm.nih.gov/pubmed/29185455
http://dx.doi.org/10.1038/s41598-017-16448-5

Ejemplares similares