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Antiphospholipid antibodies increase the levels of mitochondrial DNA in placental extracellular vesicles: Alarmin-g for preeclampsia
The pathogenesis of preeclampsia remains unclear but placental factors are known to play a crucial role causing maternal endothelial cell dysfunction. One potential factor is placental micro- and nano- vesicles. Antiphospholipid antibodies (aPL) increase the risk of preeclampsia ten-fold, in part by...
Autores principales: | Tong, Mancy, Johansson, Caroline, Xiao, Fengyi, Stone, Peter R., James, Joanna L., Chen, Qi, Cree, Lynsey M., Chamley, Lawrence W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707355/ https://www.ncbi.nlm.nih.gov/pubmed/29185455 http://dx.doi.org/10.1038/s41598-017-16448-5 |
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