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Inhibiting Rho kinase promotes goal-directed decision making and blocks habitual responding for cocaine
The prelimbic prefrontal cortex is necessary for associating actions with their consequences, enabling goal-directed decision making. We find that the strength of action–outcome conditioning correlates with dendritic spine density in prelimbic cortex, suggesting that new action–outcome learning invo...
Autores principales: | Swanson, Andrew M., DePoy, Lauren M., Gourley, Shannon L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707361/ https://www.ncbi.nlm.nih.gov/pubmed/29187752 http://dx.doi.org/10.1038/s41467-017-01915-4 |
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