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Interaction profiling of RNA-binding ubiquitin ligases reveals a link between posttranscriptional regulation and the ubiquitin system

RNA-binding ubiquitin ligases (RBULs) have the potential to link RNA-mediated mechanisms to protein ubiquitylation. Despite this, the cellular functions, substrates and interaction partners of most RBULs remain poorly characterized. Affinity purification (AP) combined with quantitative mass spectrom...

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Detalles Bibliográficos
Autores principales: Hildebrandt, Andrea, Alanis-Lobato, Gregorio, Voigt, Andrea, Zarnack, Kathi, Andrade-Navarro, Miguel A., Beli, Petra, König, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707401/
https://www.ncbi.nlm.nih.gov/pubmed/29185492
http://dx.doi.org/10.1038/s41598-017-16695-6