DHHC5-mediated palmitoylation of S1P receptor subtype 1 determines G-protein coupling

Sphingosine 1-phosphate (S1P) is a pleiotropic lipid mediator involved in the regulation of immune cell trafficking and vascular permeability acting mainly through G-protein-coupled S1P receptors (S1PRs). However, mechanism underlying how S1PRs are coupled with G-proteins remains unknown. Here we ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Badawy, Shaymaa Mohamed Mohamed, Okada, Taro, Kajimoto, Taketoshi, Ijuin, Takeshi, Nakamura, Shun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707436/
https://www.ncbi.nlm.nih.gov/pubmed/29185452
http://dx.doi.org/10.1038/s41598-017-16457-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707436/
https://www.ncbi.nlm.nih.gov/pubmed/29185452
http://dx.doi.org/10.1038/s41598-017-16457-4

Ejemplares similares