Assembly line termination in cylindrocyclophane biosynthesis: discovery of an editing type II thioesterase domain in a type I polyketide synthase

The termination step is an important source of structural diversity in polyketide biosynthesis. Most type I polyketide synthase (PKS) assembly lines are terminated by a thioesterase (TE) domain located at the C-terminus of the final module, while other PKS assembly lines lack a terminal TE domain an...

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Detalles Bibliográficos
Autores principales: Nakamura, H., Wang, J. X., Balskus, E. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707447/
https://www.ncbi.nlm.nih.gov/pubmed/29218151
http://dx.doi.org/10.1039/c4sc03132f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707447/
https://www.ncbi.nlm.nih.gov/pubmed/29218151
http://dx.doi.org/10.1039/c4sc03132f

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