Systematic re-evaluation of the bis(2-hydroxyethyl)disulfide (HEDS) assay reveals an alternative mechanism and activity of glutaredoxins

The reduction of bis(2-hydroxyethyl)disulfide (HEDS) by reduced glutathione (GSH) is the most commonly used assay to analyze the presence and properties of enzymatically active glutaredoxins (Grx), a family of central redox proteins in eukaryotes and glutathione-utilizing prokaryotes. Enzymatically...

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Detalles Bibliográficos
Autores principales: Begas, Patricia, Staudacher, Verena, Deponte, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707495/
https://www.ncbi.nlm.nih.gov/pubmed/29218148
http://dx.doi.org/10.1039/c5sc01051a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707495/
https://www.ncbi.nlm.nih.gov/pubmed/29218148
http://dx.doi.org/10.1039/c5sc01051a

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