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The Non-Homologous End Joining Protein PAXX Acts to Restrict HSV-1 Infection

Herpes simplex virus 1 (HSV-1) has extensive interactions with the host DNA damage response (DDR) machinery that can be either detrimental or beneficial to the virus. Proteins in the homologous recombination pathway are known to be required for efficient replication of the viral genome, while differ...

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Detalles Bibliográficos
Autores principales: Trigg, Ben J., Lauer, Katharina B., Fernandes dos Santos, Paula, Coleman, Heather, Balmus, Gabriel, Mansur, Daniel S., Ferguson, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707549/
https://www.ncbi.nlm.nih.gov/pubmed/29144403
http://dx.doi.org/10.3390/v9110342