ZnO Nanoparticles Protect RNA from Degradation Better than DNA

Gene therapy and RNA delivery require a nanoparticle (NP) to stabilize these nucleic acids when administered in vivo. The presence of degradative hydrolytic enzymes within these environments limits the nucleic acids’ pharmacologic activity. This study compared the effects of nanoscale ZnO and MgO in...

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Detalles Bibliográficos
Autores principales: McCall, Jayden, Smith, Joshua J., Marquardt, Kelsey N., Knight, Katelin R., Bane, Hunter, Barber, Alice, DeLong, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707595/
https://www.ncbi.nlm.nih.gov/pubmed/29117135
http://dx.doi.org/10.3390/nano7110378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707595/
https://www.ncbi.nlm.nih.gov/pubmed/29117135
http://dx.doi.org/10.3390/nano7110378

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