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ZnO Nanoparticles Protect RNA from Degradation Better than DNA
Gene therapy and RNA delivery require a nanoparticle (NP) to stabilize these nucleic acids when administered in vivo. The presence of degradative hydrolytic enzymes within these environments limits the nucleic acids’ pharmacologic activity. This study compared the effects of nanoscale ZnO and MgO in...
Autores principales: | McCall, Jayden, Smith, Joshua J., Marquardt, Kelsey N., Knight, Katelin R., Bane, Hunter, Barber, Alice, DeLong, Robert K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707595/ https://www.ncbi.nlm.nih.gov/pubmed/29117135 http://dx.doi.org/10.3390/nano7110378 |
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