Increased Loading, Efficacy and Sustained Release of Silibinin, a Poorly Soluble Drug Using Hydrophobically-Modified Chitosan Nanoparticles for Enhanced Delivery of Anticancer Drug Delivery Systems

Conventional delivery of anticancer drugs is less effective due to pharmacological drawbacks such as lack of aqueous solubility and poor cellular accumulation. This study reports the increased drug loading, therapeutic delivery, and cellular accumulation of silibinin (SLB), a poorly water-soluble ph...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuen, Cha Yee, Fakurazi, Sharida, Othman, Siti Sarah, Masarudin, Mas Jaffri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707596/
https://www.ncbi.nlm.nih.gov/pubmed/29117121
http://dx.doi.org/10.3390/nano7110379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707596/
https://www.ncbi.nlm.nih.gov/pubmed/29117121
http://dx.doi.org/10.3390/nano7110379

Ejemplares similares