Intratumoral Delivery of Doxorubicin on Folate-Conjugated Graphene Oxide by In-Situ Forming Thermo-Sensitive Hydrogel for Breast Cancer Therapy

By taking advantage of the pH-sensitive drug release property of graphene oxide (GO) after intracellular uptake, we prepared folic acid (FA)-conjugated GO (GOFA) for targeted delivery of the chemotherapeutic drug doxorubicin (DOX). GOFA-DOX was further encapsulated in an injectable in-situ forming t...

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Detalles Bibliográficos
Autores principales: Fong, Yi Teng, Chen, Chih-Hao, Chen, Jyh-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707605/
https://www.ncbi.nlm.nih.gov/pubmed/29135959
http://dx.doi.org/10.3390/nano7110388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707605/
https://www.ncbi.nlm.nih.gov/pubmed/29135959
http://dx.doi.org/10.3390/nano7110388

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