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Dietary Compound Resveratrol Is a Pan-BET Bromodomain Inhibitor

The chemopreventive and anticancer effects of resveratrol (RSV) are widely reported in the literature. Specifically, mechanisms involving epigenetic regulation are promising targets to regulate tumor development. Bromodomains act as epigenetic readers by recognizing lysine acetylation on histone tai...

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Detalles Bibliográficos
Autores principales: Dutra, Luiz Antonio, Heidenreich, David, da Silva, Gabriel Dalio Bernardes, Man Chin, Chung, Knapp, Stefan, dos Santos, Jean Leandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707644/
https://www.ncbi.nlm.nih.gov/pubmed/29077030
http://dx.doi.org/10.3390/nu9111172