Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS)

BACKGROUND: Serrated or Hyperplastic Polyposis Syndrome (SPS, HPS) is a yet poorly defined colorectal cancer (CRC) predisposition characterised by the occurrence of multiple and/or large serrated polyps throughout the colon. A serrated polyp-CRC sequence (serrated pathway) of CRC formation has been...

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Detalles Bibliográficos
Autores principales: Horpaopan, Sukanya, Kirfel, Jutta, Peters, Sophia, Kloth, Michael, Hüneburg, Robert, Altmüller, Janine, Drichel, Dmitriy, Odenthal, Margarete, Kristiansen, Glen, Strassburg, Christian, Nattermann, Jacob, Hoffmann, Per, Nürnberg, Peter, Büttner, Reinhard, Thiele, Holger, Kahl, Philip, Spier, Isabel, Aretz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707812/
https://www.ncbi.nlm.nih.gov/pubmed/29213343
http://dx.doi.org/10.1186/s13053-017-0082-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707812/
https://www.ncbi.nlm.nih.gov/pubmed/29213343
http://dx.doi.org/10.1186/s13053-017-0082-9

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