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Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling
BACKGROUND: Transcriptomic profiling of breast tumors provides opportunity for subtyping and molecular-based patient stratification. In diagnostic applications the specimen profiled should be representative of the expression profile of the whole tumor and ideally capture properties of the most aggre...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708109/ https://www.ncbi.nlm.nih.gov/pubmed/29187174 http://dx.doi.org/10.1186/s12885-017-3815-2 |