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Intra-tumor heterogeneity in breast cancer has limited impact on transcriptomic-based molecular profiling

BACKGROUND: Transcriptomic profiling of breast tumors provides opportunity for subtyping and molecular-based patient stratification. In diagnostic applications the specimen profiled should be representative of the expression profile of the whole tumor and ideally capture properties of the most aggre...

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Detalles Bibliográficos
Autores principales: Karthik, Govindasamy-Muralidharan, Rantalainen, Mattias, Stålhammar, Gustav, Lövrot, John, Ullah, Ikram, Alkodsi, Amjad, Ma, Ran, Wedlund, Lena, Lindberg, Johan, Frisell, Jan, Bergh, Jonas, Hartman, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708109/
https://www.ncbi.nlm.nih.gov/pubmed/29187174
http://dx.doi.org/10.1186/s12885-017-3815-2