Neural activity promotes long distance, target-specific regeneration of adult retinal axons

Axons in the mammalian central nervous system (CNS) fail to regenerate after injury. Here we show that if retinal ganglion cell (RGC) activity is increased by visual stimulation or using chemogenetics, their axons regenerate. We also show that if enhancement of neural activity is combined with eleva...

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Detalles Bibliográficos
Autores principales: Lim, Jung-Hwan A., Stafford, Benjamin K., Nguyen, Phong L., Lien, Brian V., Wang, Chen, Zukor, Katherine, He, Zhigang, Huberman, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708130/
https://www.ncbi.nlm.nih.gov/pubmed/27399843
http://dx.doi.org/10.1038/nn.4340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708130/
https://www.ncbi.nlm.nih.gov/pubmed/27399843
http://dx.doi.org/10.1038/nn.4340

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